
November 2001, Vol. 19 No. 6 NEW! Affymetrix Microarray Core MEMORANDUM To: Research Community From: Steven A. Goldstein, Ph.D., Associate Dean for Research & Graduate Studies, Medical School Date: September 28, 2001 Re: Affymetrix Microarray Core to be Implemented The University of Michigan implemented a contract with Affymetrix in February 2001 to provide all investigators at the University of Michigan access to the Affymetrix GeneChip® Expression Microarrays at a significant discount. It was hoped that this would allow more investigators to be able to include this new technology as part of their strategy in designing solutions to research problems. It appears that this has been quite successful. However, we also recognize that the use of this technology by more investigators is constrained by the limited access to the necessary instrumentation. Therefore, we are pleased to announce that the Medical School, with support from the Executive Vice President for Medical Affairs and the Vice President for Research, is proceeding with plans to establish a centralized Affymetrix Microarray Core. We are providing this information in the hope that it will assist you in making plans related to the use of Affymetrix microarrays in your current and/or future research initiatives. The current status of the plans to implement the Microarray Core is as follows: Instrumentation: Two fluidics units, a scanner, a workstation and analysis software have been acquired to help meet the demand of a growing group of investigators using Affymetrix GeneChip® instruments at the University. Space: Identification of space to house the new Microarray Core is being determined and a decision will be made very soon. Technical Support and Oversight: A full-time Research Assistant will be hired to process the staining and scanning of GeneChips® submitted by investigators for analysis. Dr. Robert Thompson has agreed to assist in the initial implementation of the Core. He will mentor and train the Research Assistant and serve as the Director of the Core. Dr. Dennis Martin will assist in the administration as well as some of the initial screening processes. Fees: Recharge fees will be established to cover the cost of technical support, reagents and service contracts on the instrumentation. Determination of these costs is underway. Access and Responsibility of the Investigator: The centralized core facility will initially provide hybridization and staining services, scanning services and brief introductions to data analysis. Until sufficient expertise exists within this centralized core facility, RNA isolation, purification, and probe labeling, using appropriate protocols, will be the responsibility of the investigator. Access will initially be through the existing microarray nodes most closely aligned with an investigator's research interest. It is expected that initial use will be from investigators already familiar with Affymetrix microarray applications. To be effective, investigators are strongly encouraged to develop a basic understanding of the use of microarray chips, experimental design and the specific protocols before they will be permitted to schedule experiments with the Core. Electronic versions of Affymetrix protocols will be made available. Such knowledge will be demonstrated in written proposals submitted to the Core. These proposals will be screened for appropriate experimental design. At a minimum, investigators will be required to have an appreciation for the molecular procedures necessary to obtain labeling hybridization materials, document the isolation of intact RNA (e.g. gel image) and accept responsibility for learning new data analysis software. Details of the mechanisms and guidelines are being formulated and will be communicated as they are developed. Responsibility of the Core: The Core will process samples from investigators who have been approved by the screening committee. Quality control protocols will be implemented to ensure that non-degraded samples and chips are provided before processing will be performed. As noted above, until additional molecular expertise is available, Core services will be limited to hybridization, staining and scanning services. Data Analysis: A limited number of workstations with Affymetrix data analysis software will be available to Core users. It will be the responsibility of investigators to largely self-train in the use of the software. Time-Line for Implementation: We anticipate that investigators will have access to these services in approximately two to three months. During this time the instrumentation will be installed and tested, a new Research Assistant will be hired and trained, and guidelines for access and use developed. Updates will be provided as soon as additional information is available. If you have any questions, please contact Dennis Martin in the Biomedical Research Core Facilities. He will serve as the contact for all inquiries at this time. Dennis can be reached by phone at 647-2751 or by E-mail at dennism@umich.edu Microscope Repair Service Added to MIL The new Microscope Repair Service is a collaborative effort between the Department of Cell and Developmental Biology and the Microscopy and Image-analysis Laboratory (MIL). Ms. Shelley Almburg, who has been performing microscope repair and cleaning at the University for over twelve years, will provide the service. Service hours began October 8, 2001. Shelley can be contacted at 763-1170 for appointments or contact Chris Edwards at 936-4912. New Director of Protein Core Appointed The Office of Research and Graduate Studies is pleased to announce that Dr. Henriette Remmer has been appointed Director of the Protein Structure Core in the Biomedical Research Core Facilities. Dr. Remmer was selected in a national search for candidates to replace Dr. Philip C. Andrews. Dr. Remmer received her MS in Biochemistry in 1991 from the University of Tuebingen, Germany, under the direction of Professor Guenther Jung. She received her Ph.D. in 1994 from the University of Tuebingen (Dr. Guenther Jung) and her dissertation was titled "Synthesis and Analysis of highly pure Vasoactive Intestinal Peptide (VIP) and medicinally relevant analogs. Dr. Remmer continued her training in biochemistry as a Postdoctoral Scientist in 1995 at Bachem Feinchemikalien AG, Switzerland where she focused on strategic plans and experimental procedures to elucidate specific side reactions in peptide synthesis in order to optimize large-scale synthesis. During the period of June 1996 to January 1998, Dr. Remmer served as a Postdoctoral Associate at the University of Minnesota under the direction of Dr. Gregg Fields. Her research interests during this time centered on the synthesis of a hydroxylysine derivative for Fmoc-solid phase peptide synthesis. Dr. Remmer served as the Director of Protein Services in the Protein Sciences Facility at the University of Illinois, Urbana, before coming to Michigan. In that role, she demonstrated leadership in the development and implementation of a state-of-the-art facility for the support of investigators requiring a broad range of support in all areas of protein structure. Dr. Remmer also has a Certificate of Business Administration for Scientists from the University of Illinois. Dr. Remmer is expected to begin her new appointment in November 2001. UM Faculty Elected to the Institute of Medicine! http://www.iom.edu/ The Office of Research and Graduate Studies is pleased to congratulate the following UM faculty on their election to the Institute of Medicine: George A. Kaplan, Ph.D., professor and chair, department of epidemiology, School of Public Health; Allen S. Lichter, M.D., professor of radiation oncology and dean, Medical School; Stephen J. Weiss, M.D., E. Gifford and Love Barnett Upjohn Professor of Internal Medicine and Oncology; David R. Williams, Ph.D., M.P.H., professor of sociology and senior research scientist, Survey Research Center, Institute for Social Research. Award Recipients The Office of Research and Graduate Studies congratulates Drs. Richard Ohye and Caren Goldberg, Cardiac Surgery Section, on the awarding of a Doris Duke 2001 Innovation in Clinical Research Award in Cardiovascular Diseases and Blood Disorders. The title of their research is "Outcomes of Infants with Functional Single Ventricle: A Clinical Trial of Regional Cerebral Perfusion vs Deep Hypothermic Circulatory Arrest." Look! Research Resources and Funding Opportunities http://www.med.umich.edu/medschool/faculty_staff/research.html Researchers are encouraged to visit the Research Resources web page, where there are links to internal funding opportunities as well as to sites of interest to the research community. Examples include the core facilities, grant application processing information and important policies for research investigators. The Office of Research and Graduate Studies invites users to send comments or suggestions for other links to include on the page. We want this resource to be helpful to you! Send comments to biomednews@umich.edu. Funding Opportunities 2002 Dennis W. Jahnigen Career Development Scholars Awards Deadline December 3, 2001 http://www.americangeriatrics.org/hartford/scholars_award.shtml The American Geriatrics Society announces the Jahnigen Career Development Scholars Awards. Two year grants totaling $200,000 are awarded to junior faculty physicians in the areas of anesthesiology, emergency medicine, general surgery, gynecology, ophthalmology, orthopaedic surgery, otolaryngology, physical medicine and rehabilitation, thoracic surgery, and urology. The award is intended to allow individuals to initiate and sustain a career in research and education in the geriatrics aspects of their discipline. The University of Michigan may submit ten applications, one from each speciality. Visit the Society web site for complete details. Deadline for submission of applications to the Society is January 15, 2002. For consideration as institutional nominees, submit the following by December 3, 2001: 1-2 page research summary (provide evidence on commitment to research relevant to the geriatric aspects of your specialty), CV, and a nominating letter from the department chair. Submit all internal applications to the Office of Research and Graduate Studies, 4107 Med Sci I, Box 0624 by December 3, 2001. Contact: Denise Swayze, 763-4086 or dswayze@umich.edu. The Pfizer/SWHR Scholars Grants for Faculty Development in Women's Health Internal Deadline November 15, 2001 http://www.physicianscientist.com/ The UM Medical School has been invited to submit three proposals for this grant competition. Grants of $65,000 per year for 3 years are provided to the sponsoring medical school on behalf of the Scholar. The purpose of this initiative is to provide support to promising physician-scientists who wish to conduct original research in the basic biology of serious diseases that affect women and is consistent with newer models of women's health that include and look beyond reproduction. Deadline for submission of proposals to Pfizer is December 10, 2001. For consideration as the institutional nominee, submit the following by November 15, 2001: 1-2 page research summary, CV, and a nominating letter from the department chair. Submit all internal applications to the Office of Research and Graduate Studies, 4107 Med Sci I, Box 0624 by November 15, 2001. Contact: Denise Swayze, 763-4086 or dswayze@umich.edu. Complete details on this initiative can be found on Pfizer's web site listed above. The Pfizer Scholars Grants for Faculty Development in Clinical Epidemiology Internal Deadline November 19, 2001 http://www.physicianscientist.com/ The UM Medical School has been invited to submit one proposal for this grant competition. Grants of $65,000 per year for 3 years are provided to the sponsoring medical school on behalf of the Scholar. The purpose of this initiative is to provide support for research bridging the basic science of epidemiology with clinical medicine, in order to improve both the quality of clinical research and quality of patient care. Deadline for submission of a proposal to Pfizer is December 14, 2001. For consideration as the institutional nominee, submit the following by November 19, 2001: 1-2 page research summary, CV, and a nominating letter from the department chair. Submit all internal applications to the Office of Research and Graduate Studies, 4107 Med Sci I, Box 0624 by November 19. Contact: Denise Swayze, 763-4086 or dswayze@umich.edu. Complete details on this initiative can be found on Pfizer's web site listed above. The Pfizer Postdoctoral Fellowship Grants in Biological Psychiatry–Internal Deadline December 3, 2001 http://www.physicianscientist.com/ The UM Medical School has been invited to submit one application for this grant competition. Grants of $65,000 per year for 3 years are provided to the sponsoring medical school on behalf of the Fellow. The purpose of this initiative is to provide support to promising physicians (M.D. or D.O.) who wish to conduct original research in an academic environment. Applicants must demonstrate a strong career interest in academic research in biological psychiatry. Deadline for submission of a application to Pfizer is January 11, 2002. For consideration as the institutional nominee, submit the following by December 3, 2001: 1-2 page research summary, CV, and a nominating letter from the department chair. Submit all internal applications to the Office of Research and Graduate Studies, 4107 Med Sci I, Box 0624 by December 3, 2001. Contact: Denise Swayze, 763-4086 or dswayze@umich.edu. Complete details on this initiative can be found on Pfizer's web site listed above. Rackham Interdisciplinary Collaborative Research Grant Deadline November 26, 2001 http://www.rackham.umich.edu/Faculty/RackhamIDPCollabGrant.html The Horace H. Rackham School of Graduate Studies announces a call for proposals for the Rackham Interdisciplinary Collaborative Research Grant. Awards of approximately $250,000 for use over a three-year period will be given to innovative interdisciplinary research proposals that are collaborative in nature and include graduate students as partners in the enterprise. Proposals from fields in which collaborative research is unusual and funding is limited are encouraged. There are no restrictions on the areas of research. Applicants must designate at least two Primary Investigators from different units (one must be a tenure track faculty member or research scientist). At least one of the graduate student participants must be in a Rackham degree program. Deadline for pre-proposals is November 26, 2001. Check out the Rackham web site for complete details (listed above). Special Award Opportunities University of Michigan Academic Women's Caucus–The Sarah Goddard Power Award–Deadline November 16, 2001 http://www.umich.edu/~hraa/power/ The Academic Women's Caucus requests nominations for the Sarah Goddard Power Award. The Award is given to honor members of the University community who have made achievements on behalf of women in the areas of leadership, scholarship and other activities related to their professional lives. Nominees must be affiliated with the University of Michigan and include faculty, instructors, lecturers, primary researchers, librarians, curators and senior administrative staff. Nominations may be submitted online through the Human Resources and Affirmative Action Web site at http://www.umich.edu/~hraa/power or by requesting a form from the Office of Equity and Diversity Services, 4005 Wolverine Tower at 3003 South State Street, (734) 763-0235 or TTY (734) 647-1388. Four hard copies of the nominee's CV and other supporting documents must be sent directly to Sally Grace, Room 4005 Wolverine Tower, 3003 S. State St. Ann Arbor, 48109-1281. The Albany Medical Center Prize in Medicine and Biomedical Research–Deadline January 15, 2002 http://www.amc.edu/prize_in_medicine.htm Albany Medical Center is seeking nominations for their 2002 Prize in Medicine and Biomedical Research. The purpose of the prize is to promote and recognize exceptional and sustained contributions to improving health care and advancing innovative biomedical research. The prize is $500,000 and will be presented to the recipient at an award ceremony that will take place on April 17, 2002, in Albany, New York. Any physician, scientist or group, whose work leads to notable advances in health care and scientific research with demonstrable benefits, is eligible for this prize. Nominations will be accepted through January 15, 2002. See the Center's web site for the nomination process and contact information. Seminars 47th Annual Student Biomedical Fall Research Forum The Research Forum sponsored by the Student Biomedical Research Programs (SBRP) at the Medical School and the Undergraduate Research Opportunity Program (UROP) at LS&A will take place on November 6, 2001 from 3:00-5:00 PM in the Michigan League Ballroom (2nd floor). Contact Sandy Springer at 763-6362 or sspring@umich.edu for more information. Graduate Program in Immunology, "Signal Transduction of Phagocytosis" The Graduate Program in Immunology and the Experimental Immunology Training Grant will sponsor a seminar to be held on Wednesday, November 7, 2001 from 12:00–1:00 PM in Room 5623 Med Sci II. The Speaker will be Steven Greenberg, M.D., Associate Professor, Departments of Medicine and Pharmacology, Columbia University. The topic will be "Signal Transduction of Phagocytosis." For questions or more information, contact Ellen Elkin at eelkin@umich.edu or 615-4846. Pathology Research Seminar Series The Pathology department will conduct a series of three seminars in November. All three seminars will be held from 4:30-5:30 PM in room 4234 Med Sci I: 11/05/01 "Lectins and the Investigation of Erythrocyte Polyagglutination", presented by W. John Judd, FIBMS, MIBiol, Pahtology 11/12/01 "Pathophysiology and granulomatious vasculitis" presented by Jeffrey Warren, M.D., Pathology 11/19/01 "State of the Pathology Practice", presented by Rodolfo Rasche, M.D., Pathology 3rd Annual Weisbach Lectureship in Prostate Oncology The 3rd Annual Weisbach Lectureship in Prostate Oncology titled "Clinical and Translational Studies at Dana-Farber/Harvard Cancer Center" will be presented by Philip W. Kantoff, M.D. Dr. Kantoff is Associate Professor of Medicine at Harvard Medical School and Director of the Lank Center for Genitourinary Oncology. The lecture will be held on Monday, November 19, 2001 from 12:00-1:00 p.m. in the Towsley Center Dining Room (G1320). Please RSVP to Marty Davis-Merritts at 7-3421 or medavis@umich.edu, Internal Medicine. Wiesner Symposium IV, "Braving the New World: Benefits and Challenges of Genetic Knowledge" The Office of the Vice President for Research and the Life Sciences, Values, and Society Project announce the Wiesner Symposium IV, "Braving the New World: Benefits and Challenges of Genetic Knowledge", featuring Dr. Francis Collins, Director of the National Human Genome Research Institute, as the keynote speaker. Dr. Collins will explore what the recent life science advances in genomics hold for society and research universities. The symposium will be held Friday, December 7, 2001 from 8:30 AM to 6:00 PM (keynote speaker, other speakers and panel discussions) and Saturday, December 8, 2001 from 8:30 to 12 noon (workshops). It will be held in the Hale Auditorium (room 1115) of the School of Business Administration, located on Hill Street and Tappan. The symposium and workshops are free, but registration is required. More information and on-line registration is available at: http://www.wiesner.research.umich.edu

NEW! Affymetrix Microarray Core

MEMORANDUM

To: Research Community
From: Steven A. Goldstein, Ph.D., Associate Dean for Research & Graduate Studies, Medical School
Date: September 28, 2001
Re: Affymetrix Microarray Core to be Implemented

The University of Michigan implemented a contract with Affymetrix in February 2001 to provide all investigators at the University of Michigan access to the Affymetrix GeneChip® Expression Microarrays at a significant discount. It was hoped that this would allow more investigators to be able to include this new technology as part of their strategy in designing solutions to research problems. It appears that this has been quite successful.

However, we also recognize that the use of this technology by more investigators is constrained by the limited access to the necessary instrumentation. Therefore, we are pleased to announce that the Medical School, with support from the Executive Vice President for Medical Affairs and the Vice President for Research, is proceeding with plans to establish a centralized Affymetrix Microarray Core. We are providing this information in the hope that it will assist you in making plans related to the use of Affymetrix microarrays in your current and/or future research initiatives.

The current status of the plans to implement the Microarray Core is as follows:

Instrumentation: Two fluidics units, a scanner, a workstation and analysis software have been acquired to help meet the demand of a growing group of investigators using Affymetrix GeneChip® instruments at the University.

Space: Identification of space to house the new Microarray Core is being determined and a decision will be made very soon.

Technical Support and Oversight: A full-time Research Assistant will be hired to process the staining and scanning of GeneChips® submitted by investigators for analysis. Dr. Robert Thompson has agreed to assist in the initial implementation of the Core. He will mentor and train the Research Assistant and serve as the Director of the Core. Dr. Dennis Martin will assist in the administration as well as some of the initial screening processes.

Fees: Recharge fees will be established to cover the cost of technical support, reagents and service contracts on the instrumentation. Determination of these costs is underway.

Access and Responsibility of the Investigator: The centralized core facility will initially provide hybridization and staining services, scanning services and brief introductions to data analysis. Until sufficient expertise exists within this centralized core facility, RNA isolation, purification, and probe labeling, using appropriate protocols, will be the responsibility of the investigator. Access will initially be through the existing microarray nodes most closely aligned with an investigator's research interest. It is expected that initial use will be from investigators already familiar with Affymetrix microarray applications. To be effective, investigators are strongly encouraged to develop a basic understanding of the use of microarray chips, experimental design and the specific protocols before they will be permitted to schedule experiments with the Core. Electronic versions of Affymetrix protocols will be made available. Such knowledge will be demonstrated in written proposals submitted to the Core. These proposals will be screened for appropriate experimental design. At a minimum, investigators will be required to have an appreciation for the molecular procedures necessary to obtain labeling hybridization materials, document the isolation of intact RNA (e.g. gel image) and accept responsibility for learning new data analysis software. Details of the mechanisms and guidelines are being formulated and will be communicated as they are developed.

Responsibility of the Core: The Core will process samples from investigators who have been approved by the screening committee. Quality control protocols will be implemented to ensure that non-degraded samples and chips are provided before processing will be performed. As noted above, until additional molecular expertise is available, Core services will be limited to hybridization, staining and scanning services.

Data Analysis: A limited number of workstations with Affymetrix data analysis software will be available to Core users. It will be the responsibility of investigators to largely self-train in the use of the software.

Time-Line for Implementation: We anticipate that investigators will have access to these services in approximately two to three months. During this time the instrumentation will be installed and tested, a new Research Assistant will be hired and trained, and guidelines for access and use developed. Updates will be provided as soon as additional information is available.

If you have any questions, please contact Dennis Martin in the Biomedical Research Core Facilities. He will serve as the contact for all inquiries at this time. Dennis can be reached by phone at 647-2751 or by E-mail at dennism@umich.edu

Microscope Repair Service Added to MIL

The new Microscope Repair Service is a collaborative effort between the Department of Cell and Developmental Biology and the Microscopy and Image-analysis Laboratory (MIL). Ms. Shelley Almburg, who has been performing microscope repair and cleaning at the University for over twelve years, will provide the service. Service hours began October 8, 2001. Shelley can be contacted at 763-1170 for appointments or contact Chris Edwards at 936-4912.

New Director of Protein Core Appointed

The Office of Research and Graduate Studies is pleased to announce that Dr. Henriette Remmer has been appointed Director of the Protein Structure Core in the Biomedical Research Core Facilities. Dr. Remmer was selected in a national search for candidates to replace Dr. Philip C. Andrews.

Dr. Remmer received her MS in Biochemistry in 1991 from the University of Tuebingen, Germany, under the direction of Professor Guenther Jung. She received her Ph.D. in 1994 from the University of Tuebingen (Dr. Guenther Jung) and her dissertation was titled "Synthesis and Analysis of highly pure Vasoactive Intestinal Peptide (VIP) and medicinally relevant analogs.

Dr. Remmer continued her training in biochemistry as a Postdoctoral Scientist in 1995 at Bachem Feinchemikalien AG, Switzerland where she focused on strategic plans and experimental procedures to elucidate specific side reactions in peptide synthesis in order to optimize large-scale synthesis. During the period of June 1996 to January 1998, Dr. Remmer served as a Postdoctoral Associate at the University of Minnesota under the direction of Dr. Gregg Fields. Her research interests during this time centered on the synthesis of a hydroxylysine derivative for Fmoc-solid phase peptide synthesis.

Dr. Remmer served as the Director of Protein Services in the Protein Sciences Facility at the University of Illinois, Urbana, before coming to Michigan. In that role, she demonstrated leadership in the development and implementation of a state-of-the-art facility for the support of investigators requiring a broad range of support in all areas of protein structure. Dr. Remmer also has a Certificate of Business Administration for Scientists from the University of Illinois.

Dr. Remmer is expected to begin her new appointment in November 2001.

UM Faculty Elected to the Institute of Medicine!

http://www.iom.edu/

The Office of Research and Graduate Studies is pleased to congratulate the following UM faculty on their election to the Institute of Medicine: George A. Kaplan, Ph.D., professor and chair, department of epidemiology, School of Public Health; Allen S. Lichter, M.D., professor of radiation oncology and dean, Medical School; Stephen J. Weiss, M.D., E. Gifford and Love Barnett Upjohn Professor of Internal Medicine and Oncology; David R. Williams, Ph.D., M.P.H., professor of sociology and senior research scientist, Survey Research Center, Institute for Social Research.

Award Recipients

The Office of Research and Graduate Studies congratulates Drs. Richard Ohye and Caren Goldberg, Cardiac Surgery Section, on the awarding of a Doris Duke 2001 Innovation in Clinical Research Award in Cardiovascular Diseases and Blood Disorders. The title of their research is "Outcomes of Infants with Functional Single Ventricle: A Clinical Trial of Regional Cerebral Perfusion vs Deep Hypothermic Circulatory Arrest."

Look! Research Resources and Funding Opportunities

http://www.med.umich.edu/medschool/faculty_staff/research.html

Researchers are encouraged to visit the Research Resources web page, where there are links to internal funding opportunities as well as to sites of interest to the research community. Examples include the core facilities, grant application processing information and important policies for research investigators. The Office of Research and Graduate Studies invites users to send comments or suggestions for other links to include on the page. We want this resource to be helpful to you! Send comments to biomednews@umich.edu.

Funding Opportunities

2002 Dennis W. Jahnigen Career Development Scholars Awards
Deadline December 3, 2001

http://www.americangeriatrics.org/hartford/scholars_award.shtml

The American Geriatrics Society announces the Jahnigen Career Development Scholars Awards. Two year grants totaling $200,000 are awarded to junior faculty physicians in the areas of anesthesiology, emergency medicine, general surgery, gynecology, ophthalmology, orthopaedic surgery, otolaryngology, physical medicine and rehabilitation, thoracic surgery, and urology. The award is intended to allow individuals to initiate and sustain a career in research and education in the geriatrics aspects of their discipline. The University of Michigan may submit ten applications, one from each speciality. Visit the Society web site for complete details.

Deadline for submission of applications to the Society is January 15, 2002. For consideration as institutional nominees, submit the following by December 3, 2001: 1-2 page research summary (provide evidence on commitment to research relevant to the geriatric aspects of your specialty), CV, and a nominating letter from the department chair. Submit all internal applications to the Office of Research and Graduate Studies, 4107 Med Sci I, Box 0624 by December 3, 2001. Contact: Denise Swayze, 763-4086 or dswayze@umich.edu.

The Pfizer/SWHR Scholars Grants for Faculty Development in Women's Health Internal Deadline November 15, 2001

http://www.physicianscientist.com/

The UM Medical School has been invited to submit three proposals for this grant competition. Grants of $65,000 per year for 3 years are provided to the sponsoring medical school on behalf of the Scholar. The purpose of this initiative is to provide support to promising physician-scientists who wish to conduct original research in the basic biology of serious diseases that affect women and is consistent with newer models of women's health that include and look beyond reproduction. Deadline for submission of proposals to Pfizer is December 10, 2001. For consideration as the institutional nominee, submit the following by November 15, 2001: 1-2 page research summary, CV, and a nominating letter from the department chair.

Submit all internal applications to the Office of Research and Graduate Studies, 4107 Med Sci I, Box 0624 by November 15, 2001. Contact: Denise Swayze, 763-4086 or dswayze@umich.edu. Complete details on this initiative can be found on Pfizer's web site listed above.

The Pfizer Scholars Grants for Faculty Development in Clinical Epidemiology Internal Deadline November 19, 2001

http://www.physicianscientist.com/

The UM Medical School has been invited to submit one proposal for this grant competition. Grants of $65,000 per year for 3 years are provided to the sponsoring medical school on behalf of the Scholar. The purpose of this initiative is to provide support for research bridging the basic science of epidemiology with clinical medicine, in order to improve both the quality of clinical research and quality of patient care. Deadline for submission of a proposal to Pfizer is December 14, 2001. For consideration as the institutional nominee, submit the following by November 19, 2001: 1-2 page research summary, CV, and a nominating letter from the department chair.

Submit all internal applications to the Office of Research and Graduate Studies, 4107 Med Sci I, Box 0624 by November 19. Contact: Denise Swayze, 763-4086 or dswayze@umich.edu. Complete details on this initiative can be found on Pfizer's web site listed above.

The Pfizer Postdoctoral Fellowship Grants in Biological Psychiatry–Internal Deadline December 3, 2001

http://www.physicianscientist.com/

The UM Medical School has been invited to submit one application for this grant competition. Grants of $65,000 per year for 3 years are provided to the sponsoring medical school on behalf of the Fellow. The purpose of this initiative is to provide support to promising physicians (M.D. or D.O.) who wish to conduct original research in an academic environment. Applicants must demonstrate a strong career interest in academic research in biological psychiatry. Deadline for submission of a application to Pfizer is January 11, 2002. For consideration as the institutional nominee, submit the following by December 3, 2001: 1-2 page research summary, CV, and a nominating letter from the department chair.

Submit all internal applications to the Office of Research and Graduate Studies, 4107 Med Sci I, Box 0624 by December 3, 2001. Contact: Denise Swayze, 763-4086 or dswayze@umich.edu. Complete details on this initiative can be found on Pfizer's web site listed above.

Rackham Interdisciplinary Collaborative Research Grant
Deadline November 26, 2001

http://www.rackham.umich.edu/Faculty/RackhamIDPCollabGrant.html

The Horace H. Rackham School of Graduate Studies announces a call for proposals for the Rackham Interdisciplinary Collaborative Research Grant. Awards of approximately $250,000 for use over a three-year period will be given to innovative interdisciplinary research proposals that are collaborative in nature and include graduate students as partners in the enterprise. Proposals from fields in which collaborative research is unusual and funding is limited are encouraged. There are no restrictions on the areas of research.

Applicants must designate at least two Primary Investigators from different units (one must be a tenure track faculty member or research scientist). At least one of the graduate student participants must be in a Rackham degree program. Deadline for pre-proposals is November 26, 2001. Check out the Rackham web site for complete details (listed above).

Special Award Opportunities

University of Michigan Academic Women's Caucus–The Sarah Goddard Power Award–Deadline November 16, 2001

http://www.umich.edu/~hraa/power/

The Academic Women's Caucus requests nominations for the Sarah Goddard Power Award. The Award is given to honor members of the University community who have made achievements on behalf of women in the areas of leadership, scholarship and other activities related to their professional lives. Nominees must be affiliated with the University of Michigan and include faculty, instructors, lecturers, primary researchers, librarians, curators and senior administrative staff.

Nominations may be submitted online through the Human Resources and Affirmative Action Web site at http://www.umich.edu/~hraa/power or by requesting a form from the Office of Equity and Diversity Services, 4005 Wolverine Tower at 3003 South State Street, (734) 763-0235 or TTY (734) 647-1388. Four hard copies of the nominee's CV and other supporting documents must be sent directly to Sally Grace, Room 4005 Wolverine Tower, 3003 S. State St. Ann Arbor, 48109-1281.

The Albany Medical Center Prize in Medicine and Biomedical Research–Deadline January 15, 2002

http://www.amc.edu/prize_in_medicine.htm

Albany Medical Center is seeking nominations for their 2002 Prize in Medicine and Biomedical Research. The purpose of the prize is to promote and recognize exceptional and sustained contributions to improving health care and advancing innovative biomedical research.

The prize is $500,000 and will be presented to the recipient at an award ceremony that will take place on April 17, 2002, in Albany, New York. Any physician, scientist or group, whose work leads to notable advances in health care and scientific research with demonstrable benefits, is eligible for this prize. Nominations will be accepted through January 15, 2002. See the Center's web site for the nomination process and contact information.

Seminars

47th Annual Student Biomedical Fall Research Forum

The Research Forum sponsored by the Student Biomedical Research Programs (SBRP) at the Medical School and the Undergraduate Research Opportunity Program (UROP) at LS&A will take place on November 6, 2001 from 3:00-5:00 PM in the Michigan League Ballroom (2nd floor). Contact Sandy Springer at 763-6362 or sspring@umich.edu for more information.

Graduate Program in Immunology, "Signal Transduction of Phagocytosis"

The Graduate Program in Immunology and the Experimental Immunology Training Grant will sponsor a seminar to be held on Wednesday, November 7, 2001 from 12:00–1:00 PM in Room 5623 Med Sci II. The Speaker will be Steven Greenberg, M.D., Associate Professor, Departments of Medicine and Pharmacology, Columbia University. The topic will be "Signal Transduction of Phagocytosis." For questions or more information, contact Ellen Elkin at eelkin@umich.edu or 615-4846.

Pathology Research Seminar Series

The Pathology department will conduct a series of three seminars in November. All three seminars will be held from 4:30-5:30 PM in room 4234 Med Sci I:

11/05/01 "Lectins and the Investigation of Erythrocyte Polyagglutination", presented by W. John Judd, FIBMS, MIBiol, Pahtology
11/12/01 "Pathophysiology and granulomatious vasculitis" presented by Jeffrey Warren, M.D., Pathology
11/19/01 "State of the Pathology Practice", presented by Rodolfo Rasche, M.D., Pathology

3rd Annual Weisbach Lectureship in Prostate Oncology

The 3rd Annual Weisbach Lectureship in Prostate Oncology titled "Clinical and Translational Studies at Dana-Farber/Harvard Cancer Center" will be presented by Philip W. Kantoff, M.D. Dr. Kantoff is Associate Professor of Medicine at Harvard Medical School and Director of the Lank Center for Genitourinary Oncology. The lecture will be held on Monday, November 19, 2001 from 12:00-1:00 p.m. in the Towsley Center Dining Room (G1320). Please RSVP to Marty Davis-Merritts at 7-3421 or medavis@umich.edu, Internal Medicine.

Wiesner Symposium IV, "Braving the New World: Benefits and Challenges of Genetic Knowledge"

The Office of the Vice President for Research and the Life Sciences, Values, and Society Project announce the Wiesner Symposium IV, "Braving the New World: Benefits and Challenges of Genetic Knowledge", featuring Dr. Francis Collins,
Director of the National Human Genome Research Institute, as the keynote speaker. Dr. Collins will explore what the recent life science advances in genomics hold for society and research universities.

The symposium will be held Friday, December 7, 2001 from 8:30 AM to 6:00 PM (keynote speaker, other speakers and panel discussions) and Saturday, December 8, 2001 from 8:30 to 12 noon (workshops). It will be held in the Hale Auditorium (room 1115) of the School of Business Administration, located on Hill Street and Tappan. The symposium and workshops are free, but registration is required. More information and on-line registration is available at: http://www.wiesner.research.umich.edu

November 2001, Vol. 19 No. 6

NEW! Affymetrix Microarray Core

New Director of Protein Core Appointed

UM Faculty Elected to the Institute of Medicine!

Award Recipients

Look! Research Resources and Funding Opportunities

Funding Opportunities

2002 Dennis W. Jahnigen Career Development Scholars Awards Deadline December 3, 2001

The Pfizer/SWHR Scholars Grants for Faculty Development in Women's Health Internal Deadline November 15, 2001

The Pfizer Scholars Grants for Faculty Development in Clinical Epidemiology Internal Deadline November 19, 2001

The Pfizer Postdoctoral Fellowship Grants in Biological Psychiatry–Internal Deadline December 3, 2001

Rackham Interdisciplinary Collaborative Research Grant Deadline November 26, 2001

Special Award Opportunities

University of Michigan Academic Women's Caucus–The Sarah Goddard Power Award–Deadline November 16, 2001

The Albany Medical Center Prize in Medicine and Biomedical Research–Deadline January 15, 2002

Seminars

47th Annual Student Biomedical Fall Research Forum

Graduate Program in Immunology, "Signal Transduction of Phagocytosis"

3rd Annual Weisbach Lectureship in Prostate Oncology

Wiesner Symposium IV, "Braving the New World: Benefits and Challenges of Genetic Knowledge"

2002 Dennis W. Jahnigen Career Development Scholars Awards
Deadline December 3, 2001

Rackham Interdisciplinary Collaborative Research Grant
Deadline November 26, 2001