Biosketch Directory

Dr. Goldstein completed his undergraduate education at Tufts University, receiving a B.S. Degree in Mechanical Engineering in 1976. He subsequently entered the University of Michigan and was awarded the M.S. degree in Bioengineering in 1977 and Ph.D. in Bioengineering in 1981. He joined the faculty at the University of Michigan as a Research Investigator in the Section of Orthopaedic Surgery, Department of Surgery in 1981 and became an Assistant Professor of Surgery in 1983. He was promoted to Associate Professor in the Departments of Surgery and Mechanical Engineering and Applied Mechanics in 1988 and to Professor in the Departments of Surgery, Mechanical Engineering and Applied Mechanics and Bioengineering in 1992.

Dr. Goldstein's research is in the area of orthopaedic science and focuses on connective tissue diseases, their prevention or treatment. As Director of the Orthopaedic Research Laboratories, he oversees investigations ranging from fracture repair and total joint replacement to investigating the mechanisms associated with inherited or degenerative connective tissue fragility. His primary interests relate to the investigation of the effects of metabolic or mechanical influences on bone adaptation and tissue engineering. Some of his most recent findings in mechanical adaptation of bone has also led to the development of a new artificial knee joint prosthesis which is in approval for clinical trials by the FDA, as well as to a novel approach of treating wound and tissue repair using a localized gene therapy delivery strategy. Dr. Goldstein's research is primarily supported by grants from the National Institutes of Health as well as corporate sponsors. He has published over 140 papers and chapters and has been invited to present his work at national and international symposia.

Dr. Goldstein was the recipient of the 1988 Nicholas Andre Award from the Association of Bone and Joint Surgeons and the 1989 recipient of the Kappa Delta Award from the American Academy of Orthopaedic Surgeons and the Orthopaedic Research Society for Excellence in Orthopaedic Research. He also was the recipient of the 1987 YC Fung Award for an outstanding young investigator from the American Society of Mechanical Engineering, Bioengineering Division. He currently serves on the editorial boards of four journals and is an Associate Editor of The Annals of Biomedical Engineering. He has served as the Chairman of the Orthopaedics and Musculoskeletal Science Study Section of the National Institutes of Health and holds leadership positions in several national societies.

Dr. Goldstein's current administrative appointments include Director of Orthopaedic Research (1982), Director of the Center for Biomedical Engineering Research and Associate Dean for Research and Graduate Studies (2000).

Dr. Goldstein is an active participant of the Medical School and University community through membership in Bioengineering Executive Committee (1984-present), Intellectual Properties Faculty Advisory Committee (1990-present), Conflict of Interest Committee (1993-present), Cultural Diversity Assessment Steering Committee (1995-present), Academic Outreach Intellectual Properties Task Force (1995-present) and the Organogenesis Advisory Committee (1995-present), Conflict of Interest Committee (chair 1999-present) (1993-present), Clinical Research Infrastructure Task Force (chair, 2000-present), Human Research Coordingating Committee (2000-present), Technology Transfer Advisory Committee (chair, 1998-present), Center for Integrative Genomics Advisory Committee (2000-present), Michigan Micro-Array Network Committee (2000-present).